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Ligand · DHF

DHF · Dihydrofolic acid

DHF, Dihydrofolic acid (C19 H21 N7 O6, 443.4 g/mol), in the MolNFT structures on GenesisL1: bound in 1 record (1 PDB entry). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with it.

Component
DHF
Formula
C19 H21 N7 O6
Class
ligand
Structures
1
PDB entries
1

Binding sites

DHF in 1 structure; the first of them:

  • 6MT8 · E. coli DHFR complex modeled with two ligand states · DHF A209 · binds ILE5, ALA6, ALA7, MET16, MET20, ASP27, LEU28, TRP30 and 10 more

Residues it binds most

ILE 1, ALA 1, LEU 1, MET 1, THR 1, ARG 1, ASP 1, LYS 1, PHE 1, PRO 1 (residue and the binding sites it lines).

Found with

  • THG · (6S)-5,6,7,8-tetrahydrofolate
  • MG · Magnesium ion
  • CL · Chloride ion

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