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Ligand · DAM

DAM · N-methyl-alpha-beta-dehydroalanine

DAM, N-methyl-alpha-beta-dehydroalanine (C4 H7 N O2, 101.1 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (12 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands…

Component
DAM
Formula
C4 H7 N O2
Class
ligand
Structures
12
PDB entries
12

Binding sites

DAM in 12 structures; the first of them:

  • 1EVA · NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor · DAM A7 · binds DAL1, LEU2
  • 1EVB · NMR structure of cyanobacterial toxin, phosphatase-1/-2A inhibitor · DAM A7 · binds DAL1, LEU2
  • 1FJM · Protein SERINE/THREONINE phosphatase-1 (alpha isoform, type 1) complexed with… · DAM M7 · binds VAL250, CYS273, GLY274, GLU275, DAL1, LEU2
  • 1LCM · NMR minimized average structure of microcystin-lr · DAM A7 · binds DAL1, LEU2
  • 2IAE · Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. · DAM M7 · binds LEU243, CYS269, DAL1, LEU2
  • 2IE3 · Structure of the protein phosphatase 2A core enzyme bound to tumor- inducing toxins · DAM I7 · binds LEU243, CYS269, DAL1, LEU2
  • 2NPP · Structure of the protein phosphatase 2A holoenzyme · DAM X7 · binds LEU243, CYS269, DAL1, LEU2
  • 2NYL · Crystal structure of protein phosphatase 2A (PP2A) holoenzyme with the catalytic subunit… · DAM G7 · binds LEU243, CYS269, DAL1, LEU2
  • 2NYM · Crystal structure of protein phosphatase 2A (PP2A) with C-terminus truncated catalytic… · DAM G7 · binds LEU243, CYS269, DAL1, LEU2
  • 3DW8 · Structure of a protein phosphatase 2A holoenzyme with B55 subunit · DAM G7 · binds LEU243, CYS269, DAL1, LEU2
  • 3FGA · Structural basis of PP2A and sgo interaction · DAM E7 · binds LEU243, CYS269, DAL1, LEU2
  • 5JPF · SERINE/THREONINE phosphatase Z1 (candida albicans) binds to inhibitor microcystin-lr · DAM M7 · binds VAL415, CYS438, DAL1, LEU2

Residues it binds most

LEU 18, DAL 18, CYS 15, GLU 2, GLY 2, VAL 2 (residue and the binding sites it lines).

Found with

  • 1ZN · (2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid
  • FGA · Gamma-D-glutamic acid
  • MN · Manganese (II) ion
  • BME · Beta-mercaptoethanol
  • MLI · Malonate ion

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