CZC · [(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl phosphono hydrogen phosphate

Binding sites

CZC in 7 structures; the first of them:

• 7EM2 · Crystal structure of the PI5P4Kbeta-XTP complex · CZC A501 · binds PHE139, VAL148, ARG202, ASN203, VAL204, PHE205, LYS214, ASP216 and 5 more
• 7EM5 · Crystal structure of the PI5P4Kbeta F205L-XTP complex · CZC A501 · binds PHE139, VAL148, ARG202, ASN203, VAL204, LEU205, LYS214, ASP216 and 4 more
• 7EM7 · Crystal structure of the PI5P4Kbeta N203D-XTP complex · CZC A501 · binds PHE139, VAL148, THR201, ARG202, ASP203, VAL204, PHE205, ASP216 and 4 more
• 8DHB · Active FLCN GAP complex · CZC A501 · binds LEU69, ARG70, ARG71, SER72, GLY73, LYS74, SER75, SER76 and 12 more
• 7EM2 · Crystal structure of the PI5P4KBETA-xtp complex · CZC A501 · binds PHE139, VAL148, ASN203, VAL204, PHE205, LYS214, GLU230, THR237 and 3 more
• 7EM5 · Crystal structure of the PI5P4KBETA F205L-xtp complex · CZC A501 · binds PHE139, VAL148, ASN203, VAL204, LEU205, LYS214, THR237, LEU282 and 2 more
• 7EM7 · Crystal structure of the PI5P4KBETA N203D-xtp complex · CZC A501 · binds PHE139, VAL148, ARG202, ASP203, VAL204, PHE205, THR237, LEU282 and 1 more

Residues it binds most

VAL 10, LEU 11, PHE 10, ASP 10, THR 11, ILE 11, ASN 9, ARG 6, LYS 7, SER 2 (residue and the binding sites it lines).

Found with

• CZF · [[(2~{R},3~{S},4~{R},5~{R})-5-[2,6-bis(oxidanylidene)-3~{H}-purin-9-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] phosphono hydrogen phosphate
• BEF · Beryllium trifluoride ion
• GDP · Guanosine-5'-diphosphate