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Ligand · BMZ

BMZ · 2-(2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine

BMZ, 2-(2-hydroxy-phenyl)-1H-benzoimidazole-5-carboxamidine (C14 H13 N4 O +1, 253.3 g/mol), in the MolNFT structures on GenesisL1: bound in 12 records (6 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…

Component
BMZ
Formula
C14 H13 N4 O +1
Class
ligand
Structures
12
PDB entries
6

Binding sites

BMZ in 12 structures; the first of them:

  • 1GHW · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ H246 · binds HIS57, TRP60D, LYS60F, ASP189, ALA190, CYS191, GLU192, SER195 and 7 more
  • 1GHX · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ H246 · binds HIS57, TRP60D, ASP189, ALA190, CYS191, GLU192, SER195, VAL213 and 6 more
  • 1GI0 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI1 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI3 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI8 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ B246 · binds HIS57, ASP189, SER190, CYS191, GLN192, GLY193, SER195, VAL213 and 7 more
  • 1GHW · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ H246 · binds HIS57, TRP60D, LYS60F, ASP189, ALA190, CYS191, GLU192, SER195 and 7 more
  • 1GHX · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ H246 · binds HIS57, TRP60D, ASP189, ALA190, CYS191, GLU192, SER195, VAL213 and 6 more
  • 1GI0 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI1 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI3 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ A246 · binds HIS57, ASP189, SER190, CYS191, GLN192, SER195, VAL213, SER214 and 6 more
  • 1GI8 · A novel serine protease inhibition motif involving a multi-centered short hydrogen… · BMZ B246 · binds HIS57, ASP189, SER190, CYS191, GLN192, GLY193, SER195, VAL213 and 7 more

Residues it binds most

GLY 12, SER 12, CYS 12, TRP 12, ASP 12, HIS 12, VAL 12, GLN 8, ALA 4, GLU 4 (residue and the binding sites it lines).

Found with

  • CA · Calcium ion
  • NA · Sodium ion
  • SO4 · Sulfate ion
  • MG · Magnesium ion
  • ZN · Zinc ion
  • CIT · Citric acid

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