Ligand · AMQ
AMQ · (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
AMQ, (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (C7 H10 N2 O4, 186.2 g/mol), in the MolNFT structures on GenesisL1: bound in 16 records (8 PDB entries). Every binding site with its residues within 4.5 Å, the residues it…
- Component
- AMQ
- Formula
- C7 H10 N2 O4
- Class
- ligand
- Structures
- 16
- PDB entries
- 8
Binding sites
AMQ in 16 structures; the first of them:
- 1FTM · Crystal structure of the GLUR2 ligand binding core (S1S2J) in complex with AMPA at 1.7… · AMQ A428 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 1LB8 · Crystal structure of the Non-desensitizing GluR2 ligand binding core mutant (S1S2J-L483Y)… · AMQ A427 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 6 more
- 1MY2 · crystal titration experiment (AMPA complex control) · AMQ A602 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 1P1Q · Crystal structure of the GluR2 ligand binding core (S1S2J) L650T mutant in complex with… · AMQ A602 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR138, GLY141 and 6 more
- 1P1U · Crystal structure of the GluR2 ligand-binding core (S1S2J) L650T mutant in complex with… · AMQ A302 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, GLY141, SER142 and 5 more
- 1P1W · Crystal structure of the GluR2 ligand-binding core (S1S2J) with the L483Y and L650T… · AMQ A428 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR138, GLY141 and 7 more
- 3DP4 · Crystal structure of the binding domain of the AMPA subunit GluR3 bound to AMPA · AMQ A374 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 3FAT · X-ray structure of iGluR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at… · AMQ A427 · binds GLU11, TYR59, PRO87, LEU88, THR89, ARG94, LEU136, GLY139 and 7 more
- 1FTM · Crystal structure of the GLUR2 ligand binding core (S1S2J) in complex with AMPA at 1.7… · AMQ A428 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 1LB8 · Crystal structure of the non-desensitizing GLUR2 ligand binding core mutant (S1S2J-L483Y)… · AMQ A427 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 6 more
- 1MY2 · Crystal titration experiment (AMPA complex control) · AMQ A602 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 1P1Q · Crystal structure of the GLUR2 ligand binding core (S1S2J) L650T mutant in complex with… · AMQ A602 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR138, GLY141 and 6 more
- 1P1U · Crystal structure of the GLUR2 ligand-binding core (S1S2J) L650T mutant in complex with… · AMQ A302 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, GLY141, SER142 and 5 more
- 1P1W · Crystal structure of the GLUR2 ligand-binding core (S1S2J) with the L483Y and L650T… · AMQ A428 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, THR138, GLY141 and 7 more
- 3DP4 · Crystal structure of the binding domain of the AMPA subunit GLUR3 bound to AMPA · AMQ A374 · binds GLU13, TYR61, PRO89, LEU90, THR91, ARG96, LEU138, GLY141 and 7 more
- 3FAT · X-ray structure of IGLUR4 flip ligand-binding core (S1S2) in complex with (S)-AMPA at… · AMQ A427 · binds GLU11, TYR59, PRO87, LEU88, THR89, ARG94, LEU136, GLY139 and 7 more
Residues it binds most
THR 38, LEU 38, TYR 38, GLU 38, ARG 38, GLY 38, PRO 38, SER 38, MET 36 (residue and the binding sites it lines).
Found with
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