AH2 · 1-deoxy-alpha-D-mannopyranose

Binding sites

AH2 in 9 structures; the first of them:

• 5MUC · Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol · AH2 A301 · binds PHE1, ILE13, ASN46, ASP47, TYR48, ILE52, ASP54, GLN133 and 3 more
• 6LKN · Crystal structure of ATP11C-CDC50A in PtdSer-bound E2P state · AH2 C404
• 8GYY · Bifunctional xylosidase/glucosidase LXYL with intermediate substrate xylose, 120 seconds · AH2 J3 · binds VAL772, VAL773, GLN775
• 8OJO · Galectin-3 in complex with 2,6-Anhydro-5-S-(beta-D-galactopyranosyl)-5-thio-D-altritol · AH2 A304 · binds ARG162, GLU165, GLU184, ARG186
• 9DXT · Ligand-binding and transmembrane domains of kainate receptor GluK2 in complex with… · AH2 B1007 · binds THR730
• 5MUC · Crystal structure of the fimh lectin domain in complex with 1,5- anhydromannitol · AH2 A301 · binds PHE1, ILE13, ASN46, ASP47, TYR48, ILE52, ASP54, GLN133 and 3 more
• 6LKN · Crystal structure of ATP11C-CDC50A in ptdser-bound E2P state · AH2 C404
• 7BSU · Cryo-EM structure of a human ATP11C-CDC50A flippase in ptdser-bound E2BEF state · AH2 C403
• 8CYB · SARS-cov-2 spike protein in complex with a pan-sarbecovirus nanobody 1-8 · AH2 A1312

Residues it binds most

ASP 4, ASN 4, ILE 4, PHE 4, GLN 5, TYR 4, ARG 1, GLU 1, SER 2, THR 2 (residue and the binding sites it lines).

Found with

• NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
• MG · Magnesium ion
• BMA · beta-D-mannopyranose
• MAN · alpha-D-mannopyranose
• 2J9 · 4-cyclopropyl-7-fluoro-3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide
• A1BDT · N,N'-[butane-1,4-diylbis(azanediylpropane-3,1-diyl)]bis[3-(3,4-dihydroxyphenyl)propanamide]
• BKR · Deacetyltaxol
• CLR · Cholesterol
• POV · (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• XLS · D-xylose
• YIO · 1-thio-beta-D-galactopyranose
• FUC · alpha-L-fucopyranose