GL1X · GenesisL1 explorer

Ligand · AGA

AGA · (1S)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(pentanoyloxy)methyl]ethyl octanoate

AGA, (1S)-2-{[{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy) phosphoryl]oxy}-1-[(pentanoyloxy)methyl]ethyl octanoate (C19 H36 O10 P -1, 455.5 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (3 PDB entries). Every binding site…

Component
AGA
Formula
C19 H36 O10 P -1
Class
ligand
Structures
6
PDB entries
3

Binding sites

AGA in 6 structures; the first of them:

  • 6WBV · Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc · AGA A701 · binds TYR20, LYS25, PHE26, TYR29, LEU30, SER33, ASN172, THR176 and 3 more
  • 7W7A · Heme exporter in complex with Mn-containing protoporphyrin IX, Mn-anomalous data · AGA B501 · binds GLN37, ARG220, GLN227, TYR231, VAL307, PRO312
  • 7W7B · Heme exporter HrtBA in complex with protoporphyrin IX containing manganese(III), high… · AGA B501 · binds THR33, THR36, GLN37, ARG220, LEU224, GLN227, TYR231, VAL307 and 3 more
  • 6WBV · Structure of human ferroportin bound to hepcidin and cobalt in lipid nanodisc · AGA A701 · binds TYR20, TYR29, SER33, ASN172, THR176, ARG179, ILE180, LEU183
  • 7W7A · Heme exporter in complex with mn-containing protoporphyrin IX, mn- anomalous data · AGA B501 · binds GLN37, ARG220, GLN227, TYR231, VAL307, PRO312
  • 7W7B · Heme exporter hrtba in complex with protoporphyrin IX containing MANGANESE(III), high… · AGA B501 · binds GLN37, LEU224, GLN227, TYR231, VAL307, PRO312

Residues it binds most

LEU 6, GLN 4, TYR 6, THR 5, VAL 6, ARG 5, LYS 3, PRO 4, PHE 3, SER 3 (residue and the binding sites it lines).

Found with

  • MNR · Protoporphyrin IX containing Mn
  • PEG · Di(hydroxyethyl)ether
  • PGE · Triethylene glycol
  • CO · Cobalt (II) ion
  • EDO · 1,2-ethanediol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.