8EH · (1R,2S)-N-[4-(2,6-dimethoxyphenyl)-5-(6-methylpyridin-2-yl)-1,2,4-triazol-3-yl]-1-(5-methylpyrimidin-2-yl)-1-oxidanyl-propane-2-sulfonamide

Binding sites

8EH in 4 structures; the first of them:

• 7W0L · Cryo-EM structure of a dimeric GPCR-Gi complex with small molecule · 8EH Q401 · binds TYR35, PHE78, TRP85, ILE109, PHE110, MET113, ARG168, MET183 and 8 more
• 7SUS · Crystal structure of apelin receptor in complex with small molecule · 8EH A1102 · binds PHE78, TRP85, SER106, ILE109, PHE110, ARG168, GLU198, TYR264 and 8 more
• 7W0L · Cryo-EM structure of a dimeric GPCR-gi complex with small molecule · 8EH Q401 · binds TYR35, PHE78, TRP85, ILE109, PHE110, MET113, ARG168, TRP261 and 5 more
• 7W0M · Cryo-EM structure of a monomeric GPCR-gi complex with small molecule · 8EH R401 · binds PHE78, TRP85, ILE109, PHE110, TYR264, LYS268, TYR271, PHE291 and 1 more

Residues it binds most

TYR 6, PHE 6, TRP 6, MET 5, SER 4, THR 6, ILE 5, ARG 4, LYS 4, LEU 2 (residue and the binding sites it lines).

Found with

• ZN · Zinc ion
• OLC · (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate