GL1X · GenesisL1 explorer

Ligand · 86W

86W · 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione

86W, 1,5-dimethyl-6-[2-methyl-4-[3-(trifluoromethyl)pyridin-2-yl]oxy-phenyl]pyrimidine-2,4-dione (C19 H16 F3 N3 O3, 391.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues…

Component
86W
Formula
C19 H16 F3 N3 O3
Class
ligand
Structures
2
PDB entries
1

Binding sites

86W in 2 structures; the first of them:

  • 7X2D · Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-Gs complex · 86W F502 · binds LYS81, TRP99, VAL100, ASP103, ILE104, SER107, THR108, ILE111 and 15 more
  • 7X2D · Cryo-EM structure of the tavapadon-bound D1 dopamine receptor and mini-gs complex · 86W F502 · binds LYS81, TRP99, VAL100, ASP103, ILE104, SER107, THR108, CYS186 and 10 more

Residues it binds most

SER 2, PHE 2, ASP 2, TRP 2, VAL 2, ILE 2, ASN 2, CYS 2, LEU 2, LYS 2 (residue and the binding sites it lines).

Found with

  • CLR · Cholesterol

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.