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Ligand · 7O9

7O9 · (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl) phenyl]carbonylamino]phenyl]methoxy]butanedioic acid

7O9, (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl) phenyl]carbonylamino]phenyl]methoxy]butanedioic acid (C19 H17 F3 N2 O6, 426.4 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (3 PDB entries). Every binding site…

Component
7O9
Formula
C19 H17 F3 N2 O6
Class
ligand
Structures
4
PDB entries
3

Binding sites

7O9 in 4 structures; the first of them:

  • 5MJU · Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve… · 7O9 A602 · binds ILE96, ILE100, ILE223, SER343, SER344, SER345, SER346, LEU349 and 14 more
  • 5MJU · Structure of the thermostabilized EAAT1 cryst mutant in complex with the competititve… · 7O9 A602 · binds ILE96, ILE100, ILE223, SER343, SER344, SER345, SER346, LEU349 and 14 more
  • 6S3Q · Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with tfb-tboa · 7O9 A601 · binds LEU70, ILE71, SER74, MET248, SER331, SER332, SER333, MET367 and 11 more
  • 6X14 · Inward-facing state of the glutamate transporter homologue gltph in complex with tfb-tboa · 7O9 A501 · binds ILE16, PHE50, LEU54, MET202, ALA205, ARG276, SER277, SER278 and 9 more

Residues it binds most

SER 8, THR 8, ALA 8, ILE 8, MET 8, ARG 8, LEU 8, GLY 8, ASP 8, ASN 5 (residue and the binding sites it lines).

Found with

  • 6Z6 · 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile
  • 6OU · [(2~{R})-1-[2-azanylethoxy(oxidanyl)phosphoryl]oxy-3-hexadecanoyloxy-propan-2-yl] (~{Z})-octadec-9-enoate
  • PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine
  • Y01 · Cholesterol hemisuccinate

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