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Ligand · 7JZ

7JZ · 2-deoxy-2,2-difluoro-beta-D-lyxo-hexopyranose

7JZ, 2-deoxy-2,2-difluoro-beta-D-lyxo-hexopyranose (C6 H10 F2 O5, 200.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and…

Component
7JZ
Formula
C6 H10 F2 O5
Class
sugar
Structures
4
PDB entries
2

Binding sites

7JZ in 4 structures; the first of them:

  • 3HG4 · Human alpha-galactosidase catalytic mechanism 3. Covalent intermediate · 7JZ A801 · binds TRP47, ASP92, ASP93, TYR134, CYS142, ALA143, LYS168, ASP170 and 5 more
  • 3IGU · Crystal structure of human alpha-N-acetylgalactosaminidase, covalent intermediate · 7JZ A1001 · binds TRP33, ASP78, ASP79, TYR119, CYS127, MET128, LYS154, ASP156 and 5 more
  • 3HG4 · Human alpha-galactosidase catalytic mechanism 3. covalent intermediate · 7JZ A801 · binds TRP47, ASP92, ASP93, TYR134, CYS142, ALA143, LYS168, ASP170 and 5 more
  • 3IGU · Crystal structure of human alpha-N-acetylgalactosaminidase, covalent intermediate · 7JZ A1001 · binds TRP33, ASP78, ASP79, TYR119, CYS127, MET128, LYS154, ASP156 and 5 more

Residues it binds most

ASP 8, TYR 8, ARG 8, CYS 8, LYS 8, TRP 8, MET 4, ALA 4, GLU 4, LEU 4 (residue and the binding sites it lines).

Found with

  • BMA · beta-D-mannopyranose
  • FUC · alpha-L-fucopyranose
  • MAN · alpha-D-mannopyranose
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose
  • GAL · beta-D-galactopyranose
  • SO4 · Sulfate ion
  • ACY · Acetic acid
  • GOL · Glycerol

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