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Ligand · 5RG

5RG · 2-amino-5-fluorobenzoic acid

5RG, 2-amino-5-fluorobenzoic acid (C7 H6 F N O2, 155.1 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found…

Component
5RG
Formula
C7 H6 F N O2
Class
ligand
Structures
4
PDB entries
2

Binding sites

5RG in 4 structures; the first of them:

  • 3T78 · Crystal Structure of Mycobacterium tuberculosis Indole Glycerol Phosphate Synthase (IGPS)… · 5RG A273 · binds ILE10, LYS59, SER62, PRO63, SER64, PHE98, PHE121, ASN189 and 3 more
  • 4OWN · Anthranilate phosphoribosyl transferase from Mycobacterium tuberculosis in complex with… · 5RG A404 · binds VAL106, GLY107, THR108, HIS136, GLY137, ASN138, ALA179, ARG193 and 2 more
  • 3T78 · Crystal structure of mycobacterium tuberculosis indole glycerol phosphate synthase (igps)… · 5RG A273 · binds ILE10, LYS59, SER62, PRO63, SER64, PHE98, PHE121, ASN189 and 3 more
  • 4OWN · Anthranilate phosphoribosyl transferase from mycobacterium tuberculosis in complex with… · 5RG A404 · binds VAL106, GLY107, THR108, HIS136, GLY137, ASN138, ALA179, ARG193 and 2 more

Residues it binds most

ARG 10, PRO 10, ALA 8, GLY 4, ASN 10, HIS 8, LEU 2, PHE 2, SER 2, THR 4 (residue and the binding sites it lines).

Found with

  • POP · Pyrophosphate 2-
  • PRP · 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose
  • MG · Magnesium ion
  • ACT · Acetate ion
  • GOL · Glycerol
  • IMD · Imidazole
  • MLI · Malonate ion

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