GL1X · GenesisL1 explorer

Ligand · 4RI

4RI · 6-hexyl-5-phenyl-pyrimidine-2,4-diamine

4RI, 6-hexyl-5-phenyl-pyrimidine-2,4-diamine (C16 H22 N4, 270.4 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the…

Component
4RI
Formula
C16 H22 N4
Class
ligand
Structures
3
PDB entries
2

Binding sites

4RI in 3 structures; the first of them:

  • 7XI7 · Human dihydrofolate reductase complexed with P39 · 4RI A201 · binds ILE7, VAL8, ALA9, LEU22, GLU30, PHE31, PHE34, THR56 and 6 more
  • 7FGX · Toxoplasma gondii dihydrofolate reductase thymidylate synthase (tgdhfr-ts) complexed with… · 4RI A702 · binds VAL8, VAL9, ALA10, ASP31, PHE32, PHE35, THR83, PHE91 and 3 more
  • 7XI7 · Human dihydrofolate reductase complexed with P39 · 4RI A201 · binds ILE7, VAL8, ALA9, GLU30, PHE31, PHE34, SER59, ILE60 and 3 more

Residues it binds most

VAL 6, PHE 6, THR 6, ALA 6, TYR 6, ASP 4, ILE 2, MET 3, GLU 2, LEU 2 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate
  • UMP · 2'-deoxyuridine 5'-monophosphate

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.