Ligand · 4F1
4F1 · 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid
4F1, 4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H-indazol-3-yl}benzoic acid (C22 H12 Cl F3 N2 O3, 444.8 g/mol), in the MolNFT structures on GenesisL1: bound in 6 records (5 PDB entries). Every binding site with its residues within 4.5 Å…
- Component
- 4F1
- Formula
- C22 H12 Cl F3 N2 O3
- Class
- ligand
- Structures
- 6
- PDB entries
- 5
Binding sites
4F1 in 6 structures; the first of them:
- 6T4I · ROR(gamma)t ligand binding domain in complex with cholesterol and allosteric ligand MRL871 · 4F1 A602 · binds TRP317, ALA321, LEU324, THR325, ILE328, GLN329, LEU353, LYS354 and 17 more
- 6T4I · ROR(GAMMA)T ligand binding domain in complex with cholesterol and allosteric ligand MRL871 · 4F1 A602 · binds TRP317, ALA321, LEU324, THR325, ILE328, GLN329, LEU353, LYS354 and 13 more
- 6T4K · ROR(GAMMA)T ligand binding domain in complex with desmosterol and allosteric ligand MRL871 · 4F1 A602 · binds ALA321, LEU324, THR325, ILE328, GLN329, LEU353, LYS354, MET358 and 11 more
- 6T4U · ROR(GAMMA)T ligand binding domain in complex with 20-alpha- hydroxycholesterol and… · 4F1 A803 · binds TRP317, ALA321, LEU324, THR325, ILE328, GLN329, LEU353, LYS354 and 12 more
- 6T4Y · ROR(GAMMA)T ligand binding domain in complex with 25- hydroxycholesterol and allosteric… · 4F1 A602 · binds TRP317, ALA321, LEU324, THR325, ILE328, GLN329, LEU353, LYS354 and 13 more
- 6TDC · Ppar gamma ligand binding domain in complex with mrl-871 · 4F1 A601 · binds PHE310, CYS313, GLN314, ARG316, SER317, ILE354, LEU358, MET362 and 9 more
Residues it binds most
LEU 6, ALA 5, GLN 6, PHE 6, ILE 6, MET 6, VAL 6, LYS 6, THR 5, TYR 5 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.