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Ligand · 2Y6

2Y6 · N-[(R)-(2-chlorophenyl){7-[4-(2-hydroxypropan-2-yl)pyridin-2-yl]-1-benzothiophen-2-yl}methyl]cyclopropanesulfonamide

2Y6, N-[(R)-(2-chlorophenyl){7-[4-(2-hydroxypropan-2-yl)pyridin-2-yl]-1-benzothiophen-2-yl}methyl]cyclopropanesulfonamide (C26 H25 Cl N2 O3 S2, 513.1 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…

Component
2Y6
Formula
C26 H25 Cl N2 O3 S2
Class
ligand
Structures
2
PDB entries
1

Binding sites

2Y6 in 2 structures; the first of them:

  • 4PXS · Human GKRP bound to AMG-0265 (N-[(R)-(2-CHLOROPHENYL){7-[4-(2-HYDROXYPROPAN-2-YL)… · 2Y6 A701 · binds HIS9, VAL10, ILE11, TYR24, ALA27, VAL28, PRO29, THR31 and 16 more
  • 4PXS · Human gkrp bound to amg-0265 (N-[(R)-(2-CHLOROPHENYL){7-[4-(2- hydroxypropan-2-yl)… · 2Y6 A701 · binds HIS9, VAL10, ILE11, TYR24, ALA27, VAL28, PRO29, THR31 and 16 more

Residues it binds most

ARG 4, ALA 4, ASN 4, HIS 4, MET 4, SER 4, VAL 4, ASP 4, GLU 4, GLY 4 (residue and the binding sites it lines).

Found with

  • S6P · D-sorbitol-6-phosphate
  • IOD · Iodide ion
  • SO4 · Sulfate ion
  • GOL · Glycerol

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