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Ligand · 238

238 · 6-chloro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid

238, 6-chloro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid (C23 H15 Cl F N O2, 391.8 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every binding site with its residues within 4.5 Å, the…

Component
238
Formula
C23 H15 Cl F N O2
Class
ligand
Structures
2
PDB entries
1

Binding sites

238 in 2 structures; the first of them:

  • 2PRH · The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal… · 238 A400 · binds TYR38, LEU42, MET43, LEU46, GLN47, ASP51, PRO52, ALA55 and 16 more
  • 2PRH · The structures of apo- and inhibitor bound human dihydroorotate dehydrogenase reveal… · 238 A400 · binds TYR38, LEU42, MET43, LEU46, GLN47, ASP51, PRO52, ALA55 and 16 more

Residues it binds most

LEU 2, PRO 2, ALA 2, MET 2, PHE 2, THR 2, TYR 2, VAL 2, ARG 2, ASP 2 (residue and the binding sites it lines).

Found with

  • DDQ · Decylamine-N,N-dimethyl-N-oxide
  • FMN · Flavin mononucleotide
  • ORO · Orotic acid

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