Ligand · 06U
06U · 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl) phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine
06U, 6-ethyl-5-{(3R)-3-[3-methoxy-5-(pyridin-4-yl) phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine (C22 H23 N5 O, 373.5 g/mol), in the MolNFT structures on GenesisL1: bound in 3 records (2 PDB entries). Every binding site with its residues…
- Component
- 06U
- Formula
- C22 H23 N5 O
- Class
- ligand
- Structures
- 3
- PDB entries
- 2
Binding sites
06U in 3 structures; the first of them:
- 7T7Q · R-27 In Complex with S. aureus DHFR and alpha-NADPH - Remediated for comparison with… · 06U X202 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 7 more
- 7T7Q · R-27 in complex with S. aureus DHFR and alpha-NADPH - remediated for comparison with… · 06U X202 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 7 more
- 7T7S · R-27 in complex with S. aureus DHFR and tricyclic-NADPH (tnadph) · 06U X202 · binds LEU5, VAL6, ALA7, ASN18, GLN19, LEU20, ASP27, LEU28 and 7 more
Residues it binds most
LEU 3, THR 3, VAL 3, ALA 3, ASN 3, ASP 3, GLN 3, ILE 3, PHE 3, SER 3 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.