MolNFT v2 · #225479 · RNA

Crystal structure of folE riboswitch with BH4

8XZN · RNA (53-mer): “Crystal structure of folE riboswitch with BH4”. X-ray diffraction at 1.82, 3 ligands (H4B, SPM, MG), 3 pockets (best druggability 0.62). MolNFT v2 #225479 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 8XZN
Type: RNA
Length: 53 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.82
Source: unidentified eubacterium clone A70
Molecule: RNA (53-mer)
Ligands: H4B, SPM, MG
Pockets: 3 · best druggability 0.62

Structure

x-ray diffraction · resolution 1.82 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (53-mer)	rna	53	—	—

Ligands and binding sites

H4B · 5,6,7,8-tetrahydrobiopterin · ligand · chains A
SPM · Spermine · ligand · chains A
MG · Magnesium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	475	0.62	0.77	22	H4B, MG
2	90	0.32	0.74	11	empty
3	99	0.31	0.73	13	empty

Modifications

Observed in the structure: 1 modified (nucleotide modification).

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 8XZN · PDBe 8XZN

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