MolNFT v2 · #219196 · protein

Crystal Structure of the flavoprotein monooxygenase TrlE from Streptomyces cyaneofuscatus Soc7

8RQH · Tropone 2-monooxygenase: “Crystal Structure of the flavoprotein monooxygenase TrlE from Streptomyces cyaneofuscatus Soc7”. X-ray diffraction at 2.5, 3 ligands (FAD, SO4, CL), 1 pocket (best druggability 0.91). MolNFT v2 #219196 on…

PDB: 8RQH
Type: protein
Length: 763 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.5
Source: Streptomyces cyaneofuscatus
Molecule: Tropone 2-monooxygenase
UniProt: A0A2S1JZI9
Ligands: FAD, SO4, CL
Pockets: 1 · best druggability 0.91

Structure

x-ray diffraction · resolution 2.5 · 2 distinct chains · 40% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tropone 2-monooxygenase	protein	381	41% helix, 25% strand	A0A2S1JZI9
B	Tropone 2-monooxygenase	protein	382	40% helix, 25% strand	A0A2S1JZI9

Ligands and binding sites

FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
SO4 · Sulfate ion · ion · 3 copies · chains A, B
CL · Chloride ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	985	0.91	0.93	141	FAD, CL

Interfaces

1 interface between chains.

A–B · 959 Å² buried · 5 hydrogen bonds · protein-protein

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0A2S1JZI9
Elsewhere: RCSB PDB 8RQH · PDBe 8RQH · UniProt A0A2S1JZI9

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