MolNFT v2 · #214881 · protein
The structure of HtpG M domain in complex with unstructured D131D binding site b
8K2R · Molecular chaperone HtpG (Fragment): “The structure of HtpG M domain in complex with unstructured D131D binding site b”. Solution nmr at NOT, 1 pocket (best druggability 0.54). MolNFT v2 #214881 on GenesisL1: 3D structure, binding…
- PDB
- 8K2R
- Type
- protein
- Length
- 336 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- NOT
- Source
- Escherichia coli; Staphylococcus aureus
- Molecule
- Molecular chaperone HtpG (Fragment); Disordered protein(D131D)
- UniProt
- A0A7A6VTW3, P00644
- Pockets
- 1 · best druggability 0.54
Structure
solution nmr · resolution NOT · 2 distinct chains · 32% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Molecular chaperone HtpG (Fragment) | protein | 265 | 40% helix, 21% strand | A0A7A6VTW3 |
| B | Disordered protein(D131D) | protein | 71 | 0% helix, 0% strand | P00644 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.54 | 0.89 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 2604 Ų buried · 44 hydrogen bonds · protein-protein
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7A6VTW3
- Every structure of UniProt P00644
- Elsewhere: RCSB PDB 8K2R · PDBe 8K2R · UniProt A0A7A6VTW3 · UniProt P00644
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