MolNFT v2 · #209787 · protein
Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904
8FKE: “Crystal structure of PPARgamma ligand-binding domain in complex with N-CoR peptide and inverse agonist SR32904”. X-ray diffraction at 2.02, 1 ligand (Y5T). MolNFT v2 #209787 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 8FKE
- Type
- protein
- Length
- 282 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.02
- Source
- Homo sapiens
- UniProt
- P37231, O75376
- Ligands
- Y5T
Structure
x-ray diffraction · resolution 2.02 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 268 | — | P37231 |
| D | — | protein | 14 | — | O75376 |
Ligands and binding sites
- Y5T · 2-chloro-N-(2-methylpyridin-4-yl)-5-nitrobenzamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- O75376 · AlphaFold monomer V2.0 prediction for nuclear receptor corepressor 1 (O75376) · a predicted model of the same protein · chain D against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37231
- Every structure of UniProt O75376
- Elsewhere: RCSB PDB 8FKE · PDBe 8FKE · UniProt P37231 · UniProt O75376
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