MolNFT v2 · #206585 · protein
Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering of Potent, T cell-engaging Bispecific Therapeutics
8CXC: “Novel Anti-Mesothelin Antibodies Enable Crystallography of the Intact Mesothelin Ectodo- main and Engineering…”. X-ray diffraction at 4.31. MolNFT v2 #206585 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8CXC
- Type
- protein
- Length
- 938 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.31
- Source
- Homo sapiens; Mus musculus
- UniProt
- Q13421
Structure
x-ray diffraction · resolution 4.31 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | — | protein | 212 | — | — |
| H | — | protein | 217 | — | — |
| M | — | protein | 288 | — | Q13421 |
| A | — | protein | 221 | — | — |
Compared structures
- Q13421 · AlphaFold monomer V2.0 prediction for mesothelin (Q13421) · a predicted model of the same protein · chain M against A, TM-score 0.60
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13421
- Elsewhere: RCSB PDB 8CXC · PDBe 8CXC · UniProt Q13421
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