MolNFT v2 · #205450 · protein
Human MST3 (STK24) kinase in complex with inhibitor MR39
8BZI: “Human MST3 (STK24) kinase in complex with inhibitor MR39”. X-ray diffraction at 1.72, 1 ligand (SJL). MolNFT v2 #205450 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 8BZI
- Type
- protein
- Length
- 267 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.72
- Source
- Homo sapiens
- UniProt
- Q9Y6E0
- Ligands
- SJL
Structure
x-ray diffraction · resolution 1.72 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 267 | — | Q9Y6E0 |
Ligands and binding sites
- SJL · 8-(4-azanylbutyl)-6-[2,5-bis(fluoranyl)-4-(6-methylpyridin-2-yl)phenyl]-2-(methylamino)pyrido[2,3-d]pyrimidin-7-one · ligand · chains A
- EDO · 1,2-ethanediol · additive · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q9Y6E0 · AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase 24 (Q9Y6E0) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y6E0
- Elsewhere: RCSB PDB 8BZI · PDBe 8BZI · UniProt Q9Y6E0
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