MolNFT v2 · #203392 · protein

PI3KC2a core in complex with PITCOIN1

8A9I: “PI3KC2a core in complex with PITCOIN1”. X-ray diffraction at 2.87, 2 ligands (TSW, SO4). MolNFT v2 #203392 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 8A9I
Type: protein
Length: 822 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.87
Source: Mus musculus
UniProt: Q61194
Ligands: TSW, SO4

Structure

x-ray diffraction · resolution 2.87 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	822	—	Q61194

Ligands and binding sites

TSW · 2-[4-oxidanylidene-3-(2-phenylethyl)pteridin-2-yl]sulfanyl-~{N}-(1,3-thiazol-2-yl)ethanamide · ligand · chains A
SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

8A9I · PI3KC2A core in complex with PITCOIN1 · the same entry in another collection · chain A against A, TM-score 1.00
Q61194 · AlphaFold monomer V2.0 prediction for phosphatidylinositol 4-phosphate 3-kinase C2… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q61194
Elsewhere: RCSB PDB 8A9I · PDBe 8A9I · UniProt Q61194

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