MolNFT v2 · #200232 · protein
Kras-G12D-GDP-MRTX1133 by FIB-MicroED
7XKJ: “Kras-G12D-GDP-MRTX1133 by FIB-MicroED”. Electron crystallography at 3, 3 ligands (GDP, 6IC, MG). MolNFT v2 #200232 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7XKJ
- Type
- protein
- Length
- 168 residues
- Chains
- 1
- Method
- electron crystallography
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3
- Source
- Homo sapiens
- UniProt
- A0A7J7Z4L6
- Ligands
- GDP, 6IC, MG
Structure
electron crystallography · resolution 3 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 168 | — | A0A7J7Z4L6 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A
- 6IC · 4-(4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-8-fluoro-2-{[(2R,4R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy}pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol · ligand · chains A
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A7J7Z4L6
- Elsewhere: RCSB PDB 7XKJ · PDBe 7XKJ · UniProt A0A7J7Z4L6
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