MolNFT v2 · #197202 · protein + DNA
Structure of ATP and GTP bind to Cyclic GMP AMP synthase (cGAS) through Mg coordination
7UXW: “Structure of ATP and GTP bind to Cyclic GMP AMP synthase (cGAS) through Mg coordination”. X-ray diffraction at 2.57, 4 ligands (ATP, GTP, MG). MolNFT v2 #197202 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UXW
- Type
- protein + DNA
- Length
- 763 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.57
- Source
- DNA molecule; Mus musculus
- UniProt
- Q8C6L5
- Ligands
- ATP, GTP, MG, ZN
Structure
x-ray diffraction · resolution 2.57 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 346 | — | Q8C6L5 |
| C | — | protein | 345 | — | Q8C6L5 |
| E, F, I, J | — | dna | 18 | — | — |
Ligands and binding sites
- ATP · Adenosine-5'-triphosphate · ligand · 2 copies · chains A, C
- GTP · Guanosine-5'-triphosphate · ligand · 2 copies · chains A, C
- MG · Magnesium ion · metal · 2 copies · chains A, C
- ZN · Zinc ion · metal · 2 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q8C6L5 · AlphaFold monomer V2.0 prediction for cyclic gmp-AMP synthase (Q8C6L5) · a predicted model of the same protein · chain C against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8C6L5
- Elsewhere: RCSB PDB 7UXW · PDBe 7UXW · UniProt Q8C6L5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.