MolNFT v2 · #197087 · protein
Crystal structure of aminoglycoside resistance enzyme ApmA, complex with kanamycin B and coenzyme A
7UUL: “Crystal structure of aminoglycoside resistance enzyme ApmA, complex with kanamycin B and coenzyme A”. X-ray diffraction at 2.26, 4 ligands (9CS, COA, SO4). MolNFT v2 #197087 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7UUL
- Type
- protein
- Length
- 1,648 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.26
- Source
- Staphylococcus aureus
- UniProt
- A0A1D0AST6
- Ligands
- 9CS, COA, SO4, CL
Structure
x-ray diffraction · resolution 2.26 · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 274 | — | A0A1D0AST6 |
| B, F | — | protein | 275 | — | A0A1D0AST6 |
| C | — | protein | 273 | — | A0A1D0AST6 |
| D | — | protein | 275 | — | A0A1D0AST6 |
| E | — | protein | 276 | — | A0A1D0AST6 |
Ligands and binding sites
- 9CS · (1R,2S,3S,4R,6S)-4,6-diamino-3-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-2-hydroxycyclohexyl 2,6-diamino-2,6-dideoxy-alpha-D-glucopyranoside · ligand · 6 copies · chains A, B, D, C, F, E
- COA · Coenzyme A · ligand · 5 copies · chains A, B, D, C, F, E
- SO4 · Sulfate ion · ion · 9 copies · chains A, E, B
- CL · Chloride ion · ion · chains D
- EDO · 1,2-ethanediol · additive · 10 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A1D0AST6
- Elsewhere: RCSB PDB 7UUL · PDBe 7UUL · UniProt A0A1D0AST6
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