MolNFT v2 · #196716 · protein
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411
7UJ7: “Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with RU39411”. X-ray diffraction at 1.68, 1 ligand (NYU). MolNFT v2 #196716 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7UJ7
- Type
- protein
- Length
- 872 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.68
- Source
- Homo sapiens
- UniProt
- P03372
- Ligands
- NYU
Structure
x-ray diffraction · resolution 1.68 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| D | — | protein | 223 | — | P03372 |
| B | — | protein | 222 | — | P03372 |
| A | — | protein | 216 | — | P03372 |
| C | — | protein | 211 | — | P03372 |
Ligands and binding sites
- NYU · 11alpha-{4-[2-(dimethylamino)ethoxy]phenyl}estra-1(10), 2,4-triene-3,17beta-diol · ligand · 4 copies · chains D, B, A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7UJ7 · Estrogen receptor alpha ligand binding domain Y537S mutant in complex with RU39411 · the same entry in another collection · chain D against D, TM-score 1.00
- P03372 · AlphaFold monomer V2.0 prediction for estrogen receptor (P03372) · a predicted model of the same protein · chain C against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03372
- Elsewhere: RCSB PDB 7UJ7 · PDBe 7UJ7 · UniProt P03372
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