MolNFT v2 · #192138 · protein + DNA + RNA
SpCas9 bound to TRAC off-target2 DNA substrate
7QR1: “SpCas9 bound to TRAC off-target2 DNA substrate”. X-ray diffraction at 2.6, 2 ligands (K, MG). MolNFT v2 #192138 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7QR1
- Type
- protein + DNA + RNA
- Length
- 1,447 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.6
- Source
- Streptococcus pyogenes; SYNTHETIC CONSTRUCT
- UniProt
- Q99ZW2
- Ligands
- K, MG
Structure
x-ray diffraction · resolution 2.6 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | rna | 81 | — | — |
| B | — | protein | 1328 | — | Q99ZW2 |
| C | — | dna | 28 | — | — |
| D | — | dna | 10 | — | — |
Ligands and binding sites
- K · Potassium ion · metal · 14 copies · chains A, B, C
- MG · Magnesium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- Q99ZW2 · AlphaFold monomer V2.0 prediction for CRISPR-associated endonuclease CAS9/CSN1 (Q99ZW2) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99ZW2
- Elsewhere: RCSB PDB 7QR1 · PDBe 7QR1 · UniProt Q99ZW2
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