MolNFT v2 · #191457 · protein
Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22)
7Q6W: “Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22)”. X-ray diffraction at 1.96, 2 ligands (93L, SO4). MolNFT v2 #191457 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7Q6W
- Type
- protein
- Length
- 130 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.96
- Source
- Homo sapiens
- UniProt
- Q6PL18
- Ligands
- 93L, SO4
Structure
x-ray diffraction · resolution 1.96 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 130 | — | Q6PL18 |
Ligands and binding sites
- 93L · (1R,9S)-13-[[3-methyl-8-[(1-methylpiperidin-4-yl) amino]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]carbonyl]-11,13-diazatricyclo[7.3.1.0^{2,7}]trideca-2,4,6-trien-10-one · ligand · chains A
- SO4 · Sulfate ion · ion · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7Q6W · Crystal structure of the bromodomain of ATAD2 with triazolopyridazine (cpd 22) · the same entry in another collection · chain A against A, TM-score 1.00
- Q6PL18 · AlphaFold monomer V2.0 prediction for ATPase family aaa domain- containing protein 2… · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6PL18
- Elsewhere: RCSB PDB 7Q6W · PDBe 7Q6W · UniProt Q6PL18
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