MolNFT v2 · #190944 · protein + DNA
The glucocorticoid receptor in complex with velsecorat, a PGC1a coactivator fragment and sgk 23bp
7PRW: “The glucocorticoid receptor in complex with velsecorat, a PGC1a coactivator fragment and sgk 23bp”. X-ray diffraction at 2.502, 2 ligands (82H, ZN). MolNFT v2 #190944 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7PRW
- Type
- protein + DNA
- Length
- 705 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.502
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- P04150, Q9UBK2
- Ligands
- 82H, ZN
Structure
x-ray diffraction · resolution 2.502 · 5 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 326 | — | P04150 |
| B | — | protein | 323 | — | P04150 |
| C | — | dna | 23 | — | — |
| D | — | dna | 23 | — | — |
| F | — | protein | 10 | — | Q9UBK2 |
Ligands and binding sites
- 82H · Velsecorat · ligand · 2 copies · chains A, B
- ZN · Zinc ion · metal · 4 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 6 copies · chains A, B, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- P04150 · AlphaFold monomer V2.0 prediction for glucocorticoid receptor (P04150) · a predicted model of the same protein · chain A against A, TM-score 0.78
- Q9UBK2 · AlphaFold monomer V2.0 prediction for peroxisome proliferator- activated receptor gamma… · a predicted model of the same protein · chain F against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04150
- Every structure of UniProt Q9UBK2
- Elsewhere: RCSB PDB 7PRW · PDBe 7PRW · UniProt P04150 · UniProt Q9UBK2
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