MolNFT v2 · #188817 · protein
X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 1 M NaCl
7O1W: “X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (mi307) soaked at 1 M NaCl”. X-ray diffraction at 1.8, 5 ligands (UYQ, NAG, CA). MolNFT v2 #188817 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 7O1W
- Type
- protein
- Length
- 472 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.8
- Source
- Homo sapiens
- UniProt
- P09958
- Ligands
- UYQ, NAG, CA, NA, CL
Structure
x-ray diffraction · resolution 1.8 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 472 | — | P09958 |
Ligands and binding sites
- UYQ · [[(2E)-2-[[4-[(E)-[[azaniumylidene(azanyl) methyl]hydrazinylidene]methyl]phenyl]methylidene]hydra zinyl]-azanyl-methylidene]azanium · ligand · 3 copies · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A
- CA · Calcium ion · metal · 3 copies · chains A
- NA · Sodium ion · metal · 3 copies · chains A
- CL · Chloride ion · ion · chains A
- DMS · Dimethyl sulfoxide · additive · 5 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7O1W · X-ray structure of furin in complex with the guanylhydrazone-based inhibitor 2 (MI307)… · the same entry in another collection · chain A against A, TM-score 1.00
- P09958 · AlphaFold monomer V2.0 prediction for furin (P09958) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P09958
- Elsewhere: RCSB PDB 7O1W · PDBe 7O1W · UniProt P09958
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