MolNFT v2 · #186705 · protein
HIV-1 Protease (I84V) in Complex with GS-8374
7MAB: “HIV-1 Protease (I84V) in Complex with GS-8374”. X-ray diffraction at 1.879, 2 ligands (KGQ, SO4). MolNFT v2 #186705 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7MAB
- Type
- protein
- Length
- 198 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.879
- Source
- Human immunodeficiency virus 1
- UniProt
- P03367
- Ligands
- KGQ, SO4
Structure
x-ray diffraction · resolution 1.879 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | — | protein | 99 | — | P03367 |
Ligands and binding sites
- KGQ · Diethyl ({4-[(2S,3R)-2-({[(3r,3as,6ar)-hexahydrofuro[2, 3-b]furan-3-yloxy]carbonyl}amino)-3-hydroxy-4-{isobutyl[(4-methoxyphenyl) sulfonyl]amino}butyl]phenoxy}methyl)phosphonate · ligand · chains B, A
- SO4 · Sulfate ion · ion · 5 copies · chains B, A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7MAB · HIV-1 protease (I84V) in complex with gs-8374 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03367
- Elsewhere: RCSB PDB 7MAB · PDBe 7MAB · UniProt P03367
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.