MolNFT v2 · #185986 · protein
Crystal structure of BPTF bromodomain in complex with inhibitor Pdy-3-077
7LP0: “Crystal structure of BPTF bromodomain in complex with inhibitor Pdy-3-077”. X-ray diffraction at 1.66, 1 ligand (P2L). MolNFT v2 #185986 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 7LP0
- Type
- protein
- Length
- 226 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.66
- Source
- Homo sapiens
- UniProt
- Q12830
- Ligands
- P2L
Structure
x-ray diffraction · resolution 1.66 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 111 | — | Q12830 |
| B | — | protein | 115 | — | Q12830 |
Ligands and binding sites
- P2L · 4-chlorol-2-methyl-5-[[(3~{R})-1-methylpiperidin-3-yl]amino]pyridazin-3-one · ligand · 2 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 2 copies · chains A, B
- DMS · Dimethyl sulfoxide · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7LP0 · Crystal structure of bptf bromodomain in complex with inhibitor pdy-3- 077 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q12830
- Elsewhere: RCSB PDB 7LP0 · PDBe 7LP0 · UniProt Q12830
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