MolNFT v2 · #180034 · protein

Crystal structure of CBP bromodomain liganded with 9c

7EVJ: “Crystal structure of CBP bromodomain liganded with 9c”. X-ray diffraction at 2.57, 2 ligands (JE9, PO4). MolNFT v2 #180034 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 7EVJ
Type: protein
Length: 111 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.57
Source: Homo sapiens
UniProt: Q92793
Ligands: JE9, PO4

Structure

x-ray diffraction · resolution 2.57 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	111	—	Q92793

Ligands and binding sites

JE9 · 3-acetyl-1-((3-(1-cyclopropyl-1H-pyrazol-4-yl)-2-fluoro-5-(hydroxymethyl)phenyl)carbamoyl)indolizin-7-yl dimethylcarbamate · ligand · chains A
PO4 · Phosphate ion · ion · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

7EVJ · Crystal structure of cbp bromodomain liganded with 9C · the same entry in another collection · chain A against A, TM-score 1.00
Q92793 · AlphaFold monomer V2.0 prediction for creb-binding protein (Q92793) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92793
Elsewhere: RCSB PDB 7EVJ · PDBe 7EVJ · UniProt Q92793

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