Ligand · JE9
JE9 · 3-acetyl-1-((3-(1-cyclopropyl-1H-pyrazol-4-yl)-2-fluoro-5-(hydroxymethyl)phenyl)carbamoyl)indolizin-7-yl dimethylcarbamate
JE9, 3-acetyl-1-((3-(1-cyclopropyl-1H-pyrazol-4-yl)-2-fluoro-5-(hydroxymethyl)phenyl)carbamoyl)indolizin-7-yl dimethylcarbamate (C27 H26 F N5 O5, 519.5 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB entry). Every…
- Component
- JE9
- Formula
- C27 H26 F N5 O5
- Class
- ligand
- Structures
- 2
- PDB entries
- 1
Binding sites
JE9 in 2 structures; the first of them:
- 7EVJ · Crystal structure of CBP bromodomain liganded with 9c · JE9 A1201 · binds LEU1109, PRO1110, PHE1111, GLN1113, VAL1115, LEU1120, ILE1122, TYR1167 and 3 more
- 7EVJ · Crystal structure of cbp bromodomain liganded with 9C · JE9 A1201 · binds LEU1109, PRO1110, PHE1111, GLN1113, VAL1115, LEU1120, ILE1122, TYR1167 and 3 more
Residues it binds most
LEU 2, VAL 2, ARG 2, ASN 2, GLN 2, ILE 2, PHE 2, PRO 2, TYR 2 (residue and the binding sites it lines).
Found with
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