MolNFT v2 · #179507 · protein + DNA
Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response element and Arsenic
7EEU: “Human p53 core domain with hot spot mutation R282W in complex with the natural CDKN1A(p21) p53-response…”. X-ray diffraction at 2.9, 2 ligands (ARS, ZN). MolNFT v2 #179507 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 7EEU
- Type
- protein + DNA
- Length
- 1,703 residues
- Chains
- 12
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.9
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- P04637
- Ligands
- ARS, ZN
Structure
x-ray diffraction · resolution 2.9 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, G, H | — | protein | 198 | — | P04637 |
| F | — | protein | 197 | — | P04637 |
| I, K | — | dna | 30 | — | — |
| J, L | — | dna | 30 | — | — |
Ligands and binding sites
- ARS · Arsenic · metal · 8 copies · chains A, B, C, D, E, F, G, H
- ZN · Zinc ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
- PEG · Di(hydroxyethyl)ether · additive · 2 copies · chains E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7EEU · Human P53 core domain with hot spot mutation R282W in complex with the natural… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04637
- Elsewhere: RCSB PDB 7EEU · PDBe 7EEU · UniProt P04637
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