MolNFT v2 · #177858 · protein + RNA
Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis
7CYQ: “Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate…”. Electron microscopy at 2.83, 3 ligands (GDP, ZN, MG). MolNFT v2 #177858 on GenesisL1: 3D structure, binding sites and…
- PDB
- 7CYQ
- Type
- protein + RNA
- Length
- 2,707 residues
- Chains
- 9
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.83
- Source
- Severe acute respiratory syndrome coronavirus 2; SYNTHETIC CONSTRUCT
- UniProt
- P0DTD1
- Ligands
- GDP, ZN, MG
Structure
electron microscopy · resolution 2.83 · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 926 | — | P0DTD1 |
| B | — | protein | 187 | — | P0DTD1 |
| C | — | protein | 72 | — | P0DTD1 |
| D | — | protein | 186 | — | P0DTD1 |
| I | — | rna | 25 | — | — |
| J | — | rna | 27 | — | — |
| F | — | protein | 585 | — | P0DTD1 |
| E | — | protein | 586 | — | P0DTD1 |
| G | — | protein | 113 | — | P0DTD1 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · chains A, G
- ZN · Zinc ion · metal · 8 copies · chains A, F, E
- MG · Magnesium ion · metal · chains A, G
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 7CYQ · Cryo-EM structure of an extended SARS-cov-2 replication and transcription complex reveals… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0DTD1
- Elsewhere: RCSB PDB 7CYQ · PDBe 7CYQ · UniProt P0DTD1
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