MolNFT v2 · #169632 · protein
2.1 A resolution structure of Norovirus 3CL protease in complex with inhibitor 7g
6W5L: “2.1 A resolution structure of Norovirus 3CL protease in complex with inhibitor 7g”. X-ray diffraction at 2.1, 1 ligand (T0D). MolNFT v2 #169632 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6W5L
- Type
- protein
- Length
- 660 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.1
- Source
- Norwalk virus (strain GI/Human/United States/Norwalk/1968)
- UniProt
- Q83883
- Ligands
- T0D
Structure
x-ray diffraction · resolution 2.1 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 165 | — | Q83883 |
| B | — | protein | 166 | — | Q83883 |
| C | — | protein | 162 | — | Q83883 |
| D | — | protein | 167 | — | Q83883 |
Ligands and binding sites
- T0D · (2~{S})-~{N}-[(1~{R})-1-[bis($l^{1}-oxidanyl)-methoxy-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{R})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]-2-[[[2-(3-chlorophenyl)-2-methyl-propoxy]-oxidanylidene-methyl]amino]-4-methyl-pentanamide · ligand · 4 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6W5L · 2.1 a resolution structure of norovirus 3CL protease in complex with inhibitor 7G · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q83883
- Elsewhere: RCSB PDB 6W5L · PDBe 6W5L · UniProt Q83883
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