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MolNFT v2 · #165971 · protein + RNA

Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex

6T59: “Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and…”. Electron microscopy at 3.11, 2 ligands (MG, ZN). MolNFT v2 #165971 on GenesisL1: 3D structure, binding sites and pockets in…

PDB
6T59
Type
protein + RNA
Length
11,273 residues
Chains
53
Method
electron microscopy
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
3.11
Source
Homo sapiens; Oryctolagus cuniculus
UniProt
G1TT27, G1TL06, G1SYJ6, G1SKF7, G1TUB1, G1TX33, B7NZQ2, G1TUB8, G1SZ12, G1T0C1, G1TVT6, G1SHQ2, G1T6D1, G1SE28, G1SE76, G1SQH0, G1TXF6, G1SNY0, G1SGR6, G1TDL2, G1SHG0, G1U437, G1SF08, G1U945, G1SIT5, G1TTQ5, U3KPD5, G1U001, G1TTN1, A0A087WNH4, G1U344, G1SY53, G1U7L1, G1SMR7, Q8N0Z6
Ligands
MG, ZN

Structure

electron microscopy · resolution 3.11 · 53 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A3—protein248—G1TT27
B3—protein394—G1TL06
C3—protein362——
D3—protein293—G1SYJ6
E3—protein216—G1SKF7
F3—protein225—G1TUB1
G3—protein233——
H3—protein190—G1TX33
I3—protein205—B7NZQ2
J3—protein170—G1TUB8
L3—protein210——
M3—protein138—G1SZ12
N3—protein203—G1T0C1
O3—protein199——
P3—protein153—G1TVT6
Q3—protein187——
R3—protein155——
S3—protein176——
T3—protein159—G1SHQ2
U3—protein102——
V3—protein131—G1T6D1
W3—protein63—G1SE28
X3—protein118—G1SE76
Y3—protein134—G1SQH0
Z3—protein135—G1TXF6
a3—protein147—G1SNY0
b3—protein104—G1SGR6
c3—protein98—G1TDL2
d3—protein107—G1SHG0
e3—protein128—G1U437
f3—protein109—G1SF08
g3—protein114—G1U945
h3—protein122—G1SIT5
i3—protein102—G1TTQ5
j3—protein86—U3KPD5
k3—protein69—G1U001
l3—protein50—G1TTN1
m3—protein52——
n3—protein25—A0A087WNH4
o3—protein104—G1U344
p3—protein91—G1SY53
r3—protein124—G1U7L1
s3—protein196——
t3—protein153—G1SMR7
23—rna76——
54—rna3543——
74—rna120——
84—rna151——
NI—protein29——
NA—protein54——
NB—protein58——
TT—protein426—Q8N0Z6
1—protein36——

Ligands and binding sites

  • MG · Magnesium ion · metal · 220 copies · chains P3, 54, V3, a3, g3, B3, I3, Q3, j3, C3, N3, 84, A3, F3, L3, b3, e3, X3, 74
  • ZN · Zinc ion · metal · 5 copies · chains g3, j3, m3, o3, p3

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • Q8N0Z6 · AlphaFold monomer V2.0 prediction for tetratricopeptide repeat protein 5 (Q8N0Z6) · a predicted model of the same protein · chain TT against A, TM-score 0.97

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