UniProt G1SNY0
60S ribosomal protein L27a (G1SNY0)
60S ribosomal protein L27a (UniProt G1SNY0): 70 experimental structures on GenesisL1, 4 ligands bound, 123 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- G1SNY0
- Protein
- 60S ribosomal protein L27a
- Experimental structures
- 70
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 123 · 54 records with a druggable one
Structures
70 records of G1SNY0 in the MolNFT archive: 70 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JAG | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | electron microscopy | a | — | — |
| 3JAH | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon | electron microscopy | a | — | — |
| 3JAI | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UGA stop codon | electron microscopy | a | — | — |
| 5LZS | Structure of the mammalian ribosomal elongation complex with aminoacyl-tRNA, eEF1A, and didemnin B | electron microscopy | a | MG | 2 (best 0.87) |
| 5LZT | Structure of the mammalian ribosomal termination complex with eRF1 and eRF3. | electron microscopy | a | MG | 3 (best 0.87) |
| 5LZU | Structure of the mammalian ribosomal termination complex with accommodated eRF1 | electron microscopy | a | MG | 3 (best 0.88) |
| 5LZV | Structure of the mammalian ribosomal termination complex with accommodated eRF1(AAQ) and ABCE1. | electron microscopy | a | MG | — |
| 5LZW | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a truncated mRNA. | electron microscopy | a | MG | 1 (best 0.87) |
| 5LZX | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a UGA stop codon. | electron microscopy | a | MG | — |
| 5LZY | Structure of the mammalian rescue complex with Pelota and Hbs1l assembled on a polyadenylated mRNA. | electron microscopy | a | MG | — |
| 5LZZ | Structure of the mammalian rescue complex with Pelota and Hbs1l (combined) | electron microscopy | a | MG | — |
| 6D90 | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | electron microscopy | a | — | 5 (best 0.89) |
| 6D9J | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | electron microscopy | a | — | 5 (best 0.89) |
| 6FTG | Subtomogram average of OST-containing ribosome-translocon complexes from canine rough microsomal… | electron microscopy | a | MG | 2 (best 0.87) |
| 6FTI | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S… | electron microscopy | a | MG | 2 (best 0.87) |
| 6FTJ | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Non-programmed… | electron microscopy | a | MG | — |
| 6HCJ | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | electron microscopy | a3 | MG | — |
| 6MTB | Rabbit 80S ribosome with P- and Z-site tRNAs (unrotated state) | electron microscopy | a | MG | — |
| 6MTC | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | electron microscopy | a | MG | — |
| 6MTD | Rabbit 80S ribosome with eEF2 and SERBP1 (unrotated state with 40S head swivel) | electron microscopy | a | MG | 2 (best 0.88) |
| 6MTE | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | electron microscopy | a | MG | — |
| 6P5I | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Aa | — | 2 (best 0.87) |
| 6P5J | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Aa | — | 3 (best 0.88) |
| 6P5K | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class… | electron microscopy | Aa | — | 2 (best 0.89) |
| 6P5N | Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis… | electron microscopy | Aa | — | 2 (best 0.87) |
| 6R5Q | Structure of XBP1u-paused ribosome nascent chain complex (post-state) | electron microscopy | a | MG | — |
| 6R6G | Structure of XBP1u-paused ribosome nascent chain complex with SRP. | electron microscopy | a | MG | 1 (best 0.87) |
| 6R6P | Structure of XBP1u-paused ribosome nascent chain complex (rotated state) | electron microscopy | a | MG | 3 (best 0.89) |
| 6R7Q | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | electron microscopy | a | MG | 3 (best 0.87) |
| 6SGC | Rabbit 80S ribosome stalled on a poly(A) tail | electron microscopy | a2 | MG | 1 (best 0.86) |
| 6T59 | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein… | electron microscopy | a3 | MG | — |
| 6ZVK | The Halastavi arva virus (HalV) intergenic region IRES promotes translation by the simplest… | electron microscopy | q2 | — | 1 (best 0.87) |
| 7A01 | The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible… | electron microscopy | q2 | — | 1 (best 0.86) |
| 7MDZ | 80S rabbit ribosome stalled with benzamide-CHX | electron microscopy | a | MG | 2 (best 0.87) |
| 7NFX | Mammalian ribosome nascent chain complex with SRP and SRP receptor in early state A | electron microscopy | a | — | 4 (best 0.89) |
| 7NWH | Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. | electron microscopy | a | MG | 3 (best 0.88) |
| 7O7Y | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high… | electron microscopy | Ba | SPD, MG, UNX | 2 (best 0.88) |
| 7O7Z | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot… | electron microscopy | Ba | SPD, MG, UNX | 1 (best 0.87) |
| 7O80 | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated… | electron microscopy | Ba | MG, UNX | 1 (best 0.87) |
| 7O81 | Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | electron microscopy | Ba | SPD, MG, UNX | 4 (best 0.88) |
| 7OBR | RNC-SRP early complex | electron microscopy | a | MG | 2 (best 0.88) |
| 7OYD | Cryo-EM structure of a rabbit 80S ribosome with zebrafish Dap1b | electron microscopy | a | MG | 2 (best 0.87) |
| 7QWQ | Ternary complex of ribosome nascent chain with SRP and NAC | electron microscopy | a | — | 4 (best 0.87) |
| 7QWR | Structure of the ribosome-nascent chain containing an ER signal sequence in complex with NAC | electron microscopy | a | MG | 2 (best 0.87) |
| 7QWS | Structure of ribosome translating beta-tubulin in complex with TTC5 and NAC | electron microscopy | a | MG | 2 (best 0.89) |
| 7TM3 | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the… | electron microscopy | a | MG | 1 (best 0.88) |
| 7TOQ | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR | electron microscopy | AL28 | — | 1 (best 0.86) |
| 7TOR | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 | electron microscopy | AL28 | — | — |
| 7TUT | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the… | electron microscopy | a | MG | 3 (best 0.86) |
| 7UCJ | Mammalian 80S translation initiation complex with mRNA and Harringtonine | electron microscopy | a | MG | — |
| 7UCK | 80S translation initiation complex with ac4c(-1) mRNA and Harringtonine | electron microscopy | a | MG | 2 (best 0.86) |
| 7ZJW | Rabbit 80S ribosome as it decodes the Sec-UGA codon | electron microscopy | Ld | MG, K | 2 (best 0.87) |
| 7ZJX | Rabbit 80S ribosome programmed with SECIS and SBP2 | electron microscopy | Ld | — | 1 (best 0.86) |
| 8B5L | Cryo-EM structure of ribosome-Sec61-TRAP (TRanslocon Associated Protein) translocon complex | electron microscopy | a | MG | 5 (best 0.89) |
| 8B6C | Cryo-EM structure of ribosome-Sec61 in complex with cyclotriazadisulfonamide derivative CK147 | electron microscopy | a | MG | 2 (best 0.89) |
| 8BHF | Cryo-EM structure of stalled rabbit 80S ribosomes in complex with human CCR4-NOT and CNOT4 | electron microscopy | N1 | MG | 4 (best 0.87) |
| 8BPO | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein… | electron microscopy | Z2 | MG | 4 (best 0.87) |
| 8BTK | Structure of the TRAP complex with the Sec translocon and a translating ribosome | electron microscopy | Ba | SPD, MG | 1 (best 0.87) |
| 8P2K | Ternary complex of translating ribosome, NAC and METAP1 | electron microscopy | Ba | SPD, MG, UNX | 1 (best 0.88) |
| 8RJB | Structure of the rabbit 80S ribosome stalled on a 2-TMD rhodopsin intermediate in complex with… | electron microscopy | a | MG | 1 (best 0.85) |
10 records more on the page itself.
Ligands
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