MolNFT v2 · #164177 · protein
Cryo-EM structure of the partially activated Drs2p-Cdc50p
6ROI: “Cryo-EM structure of the partially activated Drs2p-Cdc50p”. Electron microscopy at 3.7, 4 ligands (2Y5, NAG, BMA). MolNFT v2 #164177 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6ROI
- Type
- protein
- Length
- 1,447 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.7
- Source
- Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
- UniProt
- P39524, P25656
- Ligands
- 2Y5, NAG, BMA, MG
Structure
electron microscopy · resolution 3.7 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 1108 | — | P39524 |
| C | — | protein | 339 | — | P25656 |
Ligands and binding sites
- 2Y5 · (2R)-1-{[(R)-hydroxy{[(1r,2r,3r,4r,5s,6r)-2,3,5,6-tetrahydroxy-4-(phosphonooxy) cyclohexyl]oxy}phosphoryl]oxy}-3-(octadecanoyloxy) propan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate · ligand · chains A
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains C
- BMA · beta-D-mannopyranose · sugar · 2 copies
- MG · Magnesium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6ROI · Cryo-EM structure of the partially activated DRS2P-CDC50P · the same entry in another collection · chain A against A, TM-score 1.00
- P39524 · AlphaFold monomer V2.0 prediction for probable phospholipid- transporting ATPase DRS2… · a predicted model of the same protein · chain A against A, TM-score 0.99
- P25656 · AlphaFold monomer V2.0 prediction for cell division control protein 50 (P25656) · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P39524
- Every structure of UniProt P25656
- Elsewhere: RCSB PDB 6ROI · PDBe 6ROI · UniProt P39524 · UniProt P25656
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