MolNFT v2 · #164123 · protein

Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)thio]benzenesulfonamide

6RMX: “Human Carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-Dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(…”. X-ray diffraction at 1.6, 4 ligands (5DU, BEZ, ZN). MolNFT v2 #164123 on GenesisL1: 3D structure, binding sites and…

PDB: 6RMX
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.6
Source: Homo sapiens
UniProt: P00918
Ligands: 5DU, BEZ, ZN, NA

Structure

x-ray diffraction · resolution 1.6 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	257	—	P00918

Ligands and binding sites

5DU · 2-[(1S)-2,3-dihydro-1H-inden-1-ylamino]-3,5,6-trifluoro-4-[(2-hydroxyethyl)sulfanyl]benzenesulfonamide · ligand · chains A
BEZ · Benzoic acid · ligand · chains A
ZN · Zinc ion · metal · chains A
NA · Sodium ion · metal · chains A
DMS · Dimethyl sulfoxide · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6RMX · Human carbonic anhydrase II mutant T199V bound by 2-[(1S)-2,3-dihydro… · the same entry in another collection · chain A against A, TM-score 1.00
P00918 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 2 (P00918) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00918
Elsewhere: RCSB PDB 6RMX · PDBe 6RMX · UniProt P00918

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