MolNFT v2 · #161543 · protein
Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67)
6PIW: “Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67)”. X-ray diffraction at 1.9, 2 ligands (OLV, ZN). MolNFT v2 #161543 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6PIW
- Type
- protein
- Length
- 198 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- Hepacivirus C
- UniProt
- A0A0B4WYC6
- Ligands
- OLV, ZN
Structure
x-ray diffraction · resolution 1.9 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 198 | — | A0A0B4WYC6 |
Ligands and binding sites
- OLV · Cyclohexyl [(2r,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5, 16-dioxo-1,2, 3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1, 4]diazacyclopentadecin-6- yl]carbamate · ligand · chains A
- ZN · Zinc ion · metal · chains A
- EDO · 1,2-ethanediol · additive · 4 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6PIW · Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A0B4WYC6
- Elsewhere: RCSB PDB 6PIW · PDBe 6PIW · UniProt A0A0B4WYC6
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