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Ligand · OLV

OLV · Cyclohexyl [(2r,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5, 16-dioxo-1,2, 3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1, 4]diazacyclopentadecin-6- yl]carbamate

OLV, Cyclohexyl [(2r,6s,12z,13as,14ar,16as)-2-[(7-methoxy-3-methylquinoxalin-2-yl)oxy]-14A-{[(1-methylcyclopropyl)sulfonyl]carbamoyl}-5, 16-dioxo-1,2, 3,5,6,7,8,9,10,11,13A,14,14A,15,16,16A-hexadecahydrocyclopropa[e]pyrrolo[1,2-A][1…

Component
OLV
Formula
C39 H52 N6 O9 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

OLV in 2 structures; the first of them:

  • 6PIW · Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67) · OLV A1202 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 10 more
  • 6PIW · Crystal structure of HCV NS3/4A D168A protease in complex with P4-6 (NR03-67) · OLV A1202 · binds GLN1041, THR1042, PHE1043, TYR1056, HIS1057, GLY1058, VAL1078, ASP1081 and 10 more

Residues it binds most

ALA 2, GLY 2, PHE 2, SER 2, ARG 2, ASP 2, GLN 2, HIS 2, ILE 2, LEU 2 (residue and the binding sites it lines).

Found with

  • ZN · Zinc ion
  • EDO · 1,2-ethanediol

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