MolNFT v2 · #160173 · protein + DNA

Human TCF4 C-terminal bHLH domain in Complex with 13-bp Oligonucleotide Containing E-box Sequence

6OD3: “Human TCF4 C-terminal bHLH domain in Complex with 13-bp Oligonucleotide Containing E-box Sequence”. X-ray diffraction at 1.494, 1 ligand (CL). MolNFT v2 #160173 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6OD3
Type: protein + DNA
Length: 523 residues
Chains: 12
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.494
Source: Homo sapiens; SYNTHETIC CONSTRUCT
UniProt: P15884
Ligands: CL

Structure

x-ray diffraction · resolution 1.494 · 9 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, E	—	protein	62	—	P15884
B	—	protein	61	—	P15884
X, Y, Z	—	dna	13	—	—
W	—	dna	12	—	—
F	—	protein	60	—	P15884
G	—	protein	55	—	P15884
H	—	protein	61	—	P15884
I	—	protein	59	—	P15884
J	—	protein	52	—	P15884

Ligands and binding sites

CL · Chloride ion · ion · 2 copies · chains A, B, E, F
EDO · 1,2-ethanediol · additive · 11 copies · chains A, X, B, W, H, Y, Z
PG4 · Tetraethylene glycol · additive · chains J

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6OD3 · Human TCF4 C-terminal bhlh domain in complex with 13-bp oligonucleotide containing E-box… · the same entry in another collection · chain Z against Z, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15884
Elsewhere: RCSB PDB 6OD3 · PDBe 6OD3 · UniProt P15884

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