UniProt P15884
Transcription factor 4 (P15884)
Transcription factor 4 (UniProt P15884): 9 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 11 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- P15884
- Protein
- Transcription factor 4
- Experimental structures
- 9
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 11 · 3 records with a druggable one
Structures
10 records of P15884 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2KWF | The structure of E-protein activation domain 1 bound to the KIX domain of CBP/p300 elucidates… | solution nmr | B | — | — |
| 2KWF | The structure of E-protein activation domain 1 bound to the kix domain of CBP/P300 elucidates… | solution nmr | B | — | — |
| 6OD3 | Human TCF4 C-terminal bHLH domain in Complex with 13-bp Oligonucleotide Containing E-box Sequence | x-ray diffraction | A, B, E, F, G, H, I, J | CL | — |
| 6OD3 | Human TCF4 C-terminal bhlh domain in complex with 13-bp oligonucleotide containing E-box sequence | x-ray diffraction | A, B, E, F, G, H, I, J | CL | — |
| 6OD4 | Human TCF4 C-terminal bHLH domain in Complex with 11-bp Oligonucleotide Containing E-box Sequence | x-ray diffraction | A, B, G, H | — | 3 (best 0.79) |
| 6OD4 | Human TCF4 C-terminal bhlh domain in complex with 11-bp oligonucleotide containing E-box sequence | x-ray diffraction | A, B, G, H | — | — |
| 6OD5 | Human TCF4 C-terminal bHLH domain in Complex with 12-bp Oligonucleotide Containing E-box Sequence… | x-ray diffraction | A, B, C, D | CL | 5 (best 0.83) |
| 6OD5 | Human TCF4 C-terminal bhlh domain in complex with 12-bp oligonucleotide containing E-box sequence… | x-ray diffraction | A, B, C, D | CL | — |
| 8OSB | TWIST1-TCF4-ALX4 complex on specific DNA | x-ray diffraction | A | — | 3 (best 0.85) |
| P15884 | AlphaFold monomer V2.0 prediction for transcription factor 4 (P15884) | predicted | A | — | — |
Ligands
- CL · Chloride ion · in 4 records
Experiment against prediction
- 6OD5 chain D against the predicted model P15884: TM-score 0.94, RMSD 0.75 Å
- 6OD5 chain C against the predicted model P15884: TM-score 0.94, RMSD 0.69 Å
- 6OD5 chain C against the predicted model P15884: TM-score 0.94, RMSD 0.69 Å
- 6OD5 chain A against the predicted model P15884: TM-score 0.94, RMSD 0.76 Å
- 6OD5 chain A against the predicted model P15884: TM-score 0.94, RMSD 0.76 Å
- 6OD5 chain B against the predicted model P15884: TM-score 0.94, RMSD 0.74 Å
- 6OD5 chain B against the predicted model P15884: TM-score 0.94, RMSD 0.74 Å
- 6OD3 chain A against the predicted model P15884: TM-score 0.94, RMSD 0.83 Å
- 6OD3 chain A against the predicted model P15884: TM-score 0.94, RMSD 0.83 Å
- 8OSB chain A against the predicted model P15884: TM-score 0.93, RMSD 0.80 Å
Elsewhere
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