MolNFT v2 · #159878 · protein

Structure of ALDH7A1 mutant W175G complexed with NAD

6O4B: “Structure of ALDH7A1 mutant W175G complexed with NAD”. X-ray diffraction at 1.85, 2 ligands (NAD, CL). MolNFT v2 #159878 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6O4B
Type: protein
Length: 4,072 residues
Chains: 8
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.85
Source: Homo sapiens
UniProt: P49419
Ligands: NAD, CL

Structure

x-ray diffraction · resolution 1.85 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H	—	protein	509	—	P49419

Ligands and binding sites

NAD · Nicotinamide-adenine-dinucleotide · ligand · 8 copies · chains A, B, C, D, E, F, G, H
CL · Chloride ion · ion · 8 copies · chains A, B, C, D, E, F, G, H
PGE · Triethylene glycol · additive · 14 copies · chains A, B, C, D, E, F, G, H
PG4 · Tetraethylene glycol · additive · 6 copies · chains A, B, D, E, F, H
EDO · 1,2-ethanediol · additive · 5 copies · chains A, C, D, E, H
1PE · Pentaethylene glycol · additive · chains C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6O4B · Structure of ALDH7A1 mutant W175G complexed with NAD · the same entry in another collection · chain H against H, TM-score 1.00
P49419 · AlphaFold monomer V2.0 prediction for alpha-aminoadipic semialdehyde dehydrogenase… · a predicted model of the same protein · chain D against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P49419
Elsewhere: RCSB PDB 6O4B · PDBe 6O4B · UniProt P49419

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