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MolNFT v2 · #159842 · protein

Crystal structure of Frizzled 7 CRD in complex with F7.B Fab

6O3A: “Crystal structure of Frizzled 7 CRD in complex with F7.B Fab”. X-ray diffraction at 2.1, 2 ligands (NAG, NA). MolNFT v2 #159842 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6O3A
Type
protein
Length
548 residues
Chains
3
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
2.1
Source
Homo sapiens
UniProt
O75084
Ligands
NAG, NA

Structure

x-ray diffraction · resolution 2.1 · 3 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein212——
B—protein218——
E—protein118—O75084

Ligands and binding sites

  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 2 copies · chains B, E
  • NA · Sodium ion · metal · chains A
  • EDO · 1,2-ethanediol · additive · 6 copies · chains A, B, E
  • CXS · 3-cyclohexyl-1-propylsulfonic acid · additive · chains A, B, E

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6O3A · Crystal structure of frizzled 7 crd in complex with F7.B Fab · the same entry in another collection · chain A against A, TM-score 1.00
  • O75084 · AlphaFold monomer V2.0 prediction for frizzled-7 (O75084) · a predicted model of the same protein · chain E against A, TM-score 0.97

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