MolNFT v2 · #159398 · protein
Crystal structure of Akt1 (aa 123-480) kinase with a bisubstrate
6NPZ: “Crystal structure of Akt1 (aa 123-480) kinase with a bisubstrate”. X-ray diffraction at 2.12, 2 ligands (MN, VO4). MolNFT v2 #159398 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6NPZ
- Type
- protein
- Length
- 665 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.12
- Source
- Homo sapiens
- UniProt
- P31749
- Ligands
- MN, VO4
Structure
x-ray diffraction · resolution 2.12 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 322 | — | P31749 |
| B | — | protein | 323 | — | P31749 |
| F, G | — | protein | 10 | — | — |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 4 copies · chains A, B, F, G
- VO4 · Vanadate ion · ion
- PGE · Triethylene glycol · additive · 2 copies · chains A, F
- GOL · Glycerol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6NPZ · Crystal structure of AKT1 (aa 123-480) kinase with a bisubstrate · the same entry in another collection · chain A against A, TM-score 1.00
- P31749 · AlphaFold monomer V2.0 prediction for rac-alpha SERINE/THREONINE- protein kinase (P31749) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P31749
- Elsewhere: RCSB PDB 6NPZ · PDBe 6NPZ · UniProt P31749
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